Original Article

Cold Blood and Autoimmune Hematologic Disorders During Cardiopulmonary Bypass

The Duluth Clinic, Duluth, MN

^* Direct communications to: Jim Kersting, C.C.P., The Duluth Clinic, Ltd. 400 East Third Street, Duluth, MN 55805

Received: June 1982
Revised: August 1983
Accepted: February 1984

Abstract

A discussion of clinical syndromes which can result from the disorders popularly known as “cold agglutinins” is presented. Current perfusion techniques may make it increasingly necessary to remain appraised of these potential complications of cardiopulmonary bypass. The pertinent specific disorders are Cold Agglutinin Syndrome and Paroxysmal Cold Hemoglobinuria. Mechanisms of the autoimmune systems are reviewed. The relationship between perfusionist, surgical team, and the hematology laboratory in approach to potentially complicated hypothermic procedures is discussed.