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Table 1

Procedure type, patient demographics, and major morbidity.

Overall Year
p-value Missing (%)
2019 2020 2021 2022
Number of cases 40,777 10,261 9295 9731 11,490
Number of hospitals 42 38 38 38 42
Number of cases/center, median (IQR) 181.5 (121.8, 277.2) 197.5 (131.0, 295.5) 168.0 (112.8, 234.2) 178.0 (108.0, 272.0) 194.5 (127.2, 308.0)
Procedure type <0.001
 Valve 6780 (16.6) 1785 (17.4) 1492 (16.1) 1557 (16.0) 1946 (16.9)
  PredMM#, median (%) 9.6 [6.2, 16.6] (n = 6780) 9.6 [6.3, 16.7] 9.7 [6.2, 16.7] 9.6 [6.2, 16.3] 9.5 [6.2, 16.5]
 CABG 22,406 (54.9) 5454 (53.2) 5118 (55.1) 5586 (57.4) 6248 (54.4)
  PredMM#, median (%) 8.4 [5.7, 13.3] (n = 22,406) 8.5 [5.8, 13.7] 8.5 [5.8, 13.5] 8.3 [5.6, 13.4] 8.2 [5.6, 12.9]
 CABG+Valve 3217 (7.9) 928 (9.0) 715 (7.7) 709 (7.3) 865 (7.5)
  PredMM#, median (%) 18.1 [12.9, 26.8] (n = 3217) 17.9 [12.9, 26.1] 18.9 [13.3, 29.2] 17.7 [12.8, 26.5] 18.1 [12.5, 26.4]
 Other 8374 (20.5) 2094 (20.4) 1970 (21.2) 1879 (19.3) 2431 (21.2)
  PredMM#, median (%) 4.8 [3.8, 5.9] (n = 8374) 3.4 [3.4, 3.4] 6.2 [4.3, 7.4] 4.8 [4.8, 4.8] 4.80 [3.9, 5.7]
Demographics
 Gender 0.66
  Male 29,198 (71.6) 7361 (71.7) 6692 (72.0) 6961 (71.5) 8184 (71.2)
  Female 11,579 (28.4) 2900 (28.3) 2603 (28.0) 2770 (28.5) 3306 (28.8)
  Unknown 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Age, median 66.0 [58.0, 73.0] 66.0 [58.0, 72.0] 66.0 [58.0, 73.0] 66.0 [58.0, 73.0] 66.0 [58.0, 73.0] 0.50 0.5
 Race <0.001 0
  Caucasian 32,902 (80.7) 8053 (78.5) 7409 (79.7) 8091 (83.1) 9349 (81.4)
  Black 3505 (8.6) 982 (9.6) 763 (8.2) 809 (8.3) 951 (8.3)
  Other 2202 (5.4) 475 (4.6) 436 (4.7) 550 (5.7) 741 (6.4)
  Unknown 2168 (5.3) 751 (7.3) 687 (7.4) 281 (2.9) 449 (3.9)
Risk factors
 Diabetes 15,962 (39.1) 3945 (38.4) 3618 (38.9) 3984 (40.9) 4415 (38.4) <0.001 0
 Peripheral arterial disease 5072 (12.4) 1349 (13.1) 1209 (13.0) 1152 (11.8) 1362 (11.9) 0.003 0
 Cerebrovascular disease 9336 (22.9) 2402 (23.4) 2208 (23.8) 2214 (22.8) 2512 (21.9) 0.006 0
 Chronic lung disease moderate/severe 4391 (10.8) 1044 (10.2) 950 (10.2) 1136 (11.7) 1261 (11.0) 0.002 0.1
White blood cell count 0.003 0
  <4.5 2014 (4.9) 505 (4.9) 412 (4.4) 482 (5.0) 615 (5.4)
  4.5–10 32,268 (79.1) 8104 (79.0) 7306 (78.6) 7760 (79.7) 9098 (79.2)
  >10 6495 (15.9) 1652 (16.1) 1577 (17.0) 1489 (15.3) 1777 (15.5)
 New York Heart Association Class III/IV 6512 (16.0) 1613 (15.7) 1312 (14.1) 1642 (16.9) 1945 (16.9) <0.001 0
 Previous myocardial infarction 16,496 (40.5) 4192 (40.9) 3861 (41.5) 3856 (39.6) 4587 (39.9) 0.025 0
 First cardiac surgery 37,741 (92.6) 9471 (92.3) 8582 (92.3) 9060 (93.1) 10,628 (92.5) 0.11 0
 Ejection fraction, median 58.0 [49.0, 63.0] 58.0 [48.0, 63.0] 57.5 [48.0, 63.0] 58.0 [50.0, 63.0] 58.0 [50.0, 63.0] <0.001 1.5
 Ejection fraction <0.001 0
  <40 5317 (13.0) 1393 (13.6) 1350 (14.5) 1235 (12.7) 1339 (11.7)
  40–50 4802 (11.8) 1243 (12.1) 1116 (12.0) 1141 (11.7) 1302 (11.3)
  50–60 13,732 (33.7) 3127 (30.5) 3133 (33.7) 3354 (34.5) 4118 (35.8)
  ≥60 16,926 (41.5) 4498 (43.8) 3696 (39.8) 4001 (41.1) 4731 (41.2)
 Number of diseased vessel (3 or more) 20,677 (50.7) 5196 (50.6) 4769 (51.3) 5043 (51.8) 5669 (49.3) 0.002 0
 Current smoker 7728 (19.0) 1851 (18.0) 1878 (20.2) 1836 (18.9) 2163 (18.8) 0.002 0
 Cardiogenic shock 1247 (3.1) 335 (3.3) 283 (3.0) 298 (3.1) 331 (2.9) 0.44 0
 Status <0.001 0
  Elective 21,504 (52.7) 5281 (51.5) 4557 (49.0) 5326 (54.7) 6340 (55.2)
  Urgent 17,625 (43.2) 4544 (44.3) 4324 (46.5) 4035 (41.5) 4722 (41.1)
  Emergent/emergent salvage 1648 (4.0) 436 (4.2) 414 (4.5) 370 (3.8) 428 (3.7)
Morbidity/mortality
  Major morbidity (%) 6240 (34.2) 1508 (33.3) 1553 (36.3) 1418 (33.2) 1761 (34.0) 0.008 0
  Operative mortality (%) 1349 (3.3%) 321 (3.1%) 339 (3.6%) 331 (3.4%) 358 (3.1%) 0.12 0

Continuous variables are expressed as median, [IQR], and categorical variables as count (%). PredMM#, Predicted Risk of Mortality and Morbidity. Major morbidity (stroke/cerebrovascular accident, surgical re-exploration, deep sternal wound infection, postoperative renal failure, prolonged intubation).

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