Table 7
Subgroup analysis: Intraoperative variables for aortic cross-clamp time greater than 120 min.
Variable | HKB | DNC | p-value |
---|---|---|---|
N | 64 | 64 | |
Procedure type | |||
CABG | 5 (8%) | 3 (5%) | 0.77 |
Aortic/Dissection | 5 (8%) | 9 (14%) | |
Other | 6 (9%) | 5 (8%) | |
Valve | 33 (52%) | 31 (48%) | |
Valve/CABG | 15 (23%) | 16 (25%) | |
CPB time (min) | 185 (160, 210) | 190 (166, 217) | 0.69 |
AXC time (min) | 146 (129, 165) | 143 (130, 173) | 0.98 |
Total procedure time (min) | 294 (248, 332) | 322 (271, 375) | 0.015 |
Hemofiltration requirement | 0 (0%) | 4 (6%) | 0.12 |
Fluid output (mL) | 400 (200, 750) | 460 (250, 1188) | 0.35 |
Minimum haemoglobin (g/L) | 91 (77, 103) | 91 (76, 101) | 0.75 |
Minimum cardioplegia temperature (°C) | 31 (30, 31) | 5 (5, 6) | <0.001 |
Total cardioplegia volume delivered (mL) | 2129 (1950, 2486) | 1523 (1007, 2009) | <0.001 |
Cardioplegia delivery route | |||
Antegrade | 30 (47%) | 43 (67%) | 0.031 |
Retrograde | 0 (0%) | 1 (2%) | |
Antegrade + Retrograde | 34 (53%) | 20 (31%) | |
Number of cardioplegia doses | 7 (6, 8) | 2 (1, 4) | <0.001 |
Spontaneous recovery of rhythm | 36 (56%) | 56 (89%) | <0.001 |
Maximum ischemic time (min) | 32 (29, 39) | 101 (87, 119) | <0.001 |
Peak creatinine on pump (umol/L) | 101 (76, 135) | 103 (83, 165) | 0.22 |
Last haemoglobin on pump (g/L) | 93 (80, 104) | 94 (86, 105) | 0.36 |
Continuous variables are expressed median (IQR), categorical variables are expressed number (%). Abbreviation: Abbreviation: HKB – hyperkalaemic blood cardioplegia; DNC – Del Nido cardioplegia; CABG – coronary artery bypass graft; CPB – cardiopulmonary bypass; AXC – aortic cross-clamp.
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