Between-group comparison of the lactate dehydrogenase (LDH) and CPK-MB demonstrated significant differences between two groups at post-operative time. The post-operative value was significantly higher in the Trial group receiving modified del Nido solution based on lactated Ringer’s solution (LR DL) compared with the standard del Nido solution based on Plasma-Lyte A (PL DL). Presented p-values were calculated using analysis of covariance (ANCOVA) with Bonferroni adjustment with values for the baseline (preoperative) amounts of LDH (A) and CPK-MB (B) set as covariates to adjust for the differences in the baseline between two groups. # p < 0.05 vs. the PL DN group at the same time, & p < 0.05 vs. the baseline (preop) in the same group, ** p < 0.001 compared with the baseline in the same group.