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Table 1

del Nido (DN) cardioplegia solution’s components and the modified formula.

Modified DN Standard DN solution
Carrier Ringer’s Lactated solution (Sodium 130 mEq/liter; Potassium 4 mEq/liter; Calcium 3 mEq/liter; Chloride 110 mEq/liter; Lactate (CH3CH(OH)COO−) 28 mEq/liter) Plasma-Lyte A (sodium 140 mmol/L, potassium 5 mmol/L, magnesium 1.5 mmol/L, chloride 98 mmol/L, acetate 27 mmol/L, gluconate 23 mmol/L), 1000 mL
KCl 26 mEq 26 mEq
NaHCO3 13 mEq 13 mEq
Mannitol 3.26 g 3.26 g
Lidocaine 130 mg 130 mg
Final volume 1100 mL 1100 mL
Blood: carrier ratio 1:4 1:4
pH 6.2 (6.0–7.5) 7.4 (6.5–8.0)
Dosage and administration Initial arrest by a dose of 20 mL∙kg−1 and subsequent 10 mL∙kg−1 re-dosing after 90 min Initial arrest by a dose of 20 mL∙kg−1 and subsequent 10 mL∙kg−1 re-dosing after 90 min

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