Table 2
Pre and post MCS cannulation biomarker kinetics.
| Biomarker | Pre-cannulation, N = 141 | Post-cannulation, N = 141 | P-value2 |
|---|---|---|---|
| Trem 1 (ng/L) | 446 (122, 245, 549, 1354) [488, 339] | 371 (183, 264, 463, 898) [390, 185] | 0.6 |
| Presepsin (pg/mL) | 39,630 (4477, 25,142, 73,225, 318,592) [73,539, 87,577] | 46,498 (6267, 24,368, 142,630, 1,059,987) [157,420, 285,461] | 0.5 |
| CRP (mg/mL) | 31 (1, 1, 112, 676) [111, 196] | 61 (19, 44, 187, 632) [131, 167] | 0.2 |
| PCT (ng/mL) | 0 (0, 0, 1, 94) [7, 25] | 1 (0, 0, 2, 57) [5, 15] | 0.4 |
Legend: 1Median (Minimum, Interquartile Range, Maximum) [Mean, Standard Deviation], 2Wilcoxon rank sum exact test; Wilcoxon rank sum test. Soluble Triggering Receptor expressed on Myeloid cells (sTREM-1), C-Reactive Protein (CRP). N is 14 as 4 patients either developed an infection in the first 48 h of mechanical circulatory support or did not have a pre and post cannulation residual sample available for analysis. Due to the use of residual samples, there were some instances of patients missing samples.
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