Table 3
Biomarker values while on mechanical circulatory support.
| Biomarker | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
|---|---|---|---|---|---|
| N = 141 | N = 131 | N = 101 | N = 91 | N = 92 | |
| sTREM-1 (ng/L) | 371 (183, 264, 463, 898) [390, 185] | 367 (120, 325, 498, 1054) [434, 270] | 392 (141, 227, 576, 815) [427, 243] | 421 (154, 359, 531, 738) [435, 190] | 314 (160, 185, 629 880) [435, 277] |
| Presepsin (pg/mL) | 46,498 (6267, 24,368, 142,630, 1,059,987) [157,420, 285,461] | 62,389 (8476, 26,010, 100,297, 1,059,987) [155,675, 294,245] | 39,496 (12,916, 24,411, 66,552, 396,664) [82,683, 120,826] | 31,986 (15,155, 27,876, 82,103, 191,587) [61,354, 58,766] | 27,453 (11,537, 15,197, 88,020, 143,358) [55,680, 54,380] |
| CRP (mg/mL) | 61 (19, 44, 187, 632) [131, 167] | 112 (41, 80, 316, 544) [196, 168] | 119 (21, 77, 236, 556) [194, 191] | 90 (13, 45, 166, 544) [171, 191] | 80 (23, 40, 288, 1016) [252, 354] |
| PCT (ng/mL) | 1 (0, 0, 2, 57) [5, 15] | 1 (0, 0, 2, 189) [16, 52] | 0.78 (0.05, 0.42, 1.31, 5.26) [1.19, 1.52] | 0.34 (0.03, 0.06, 1.34, 2.96) [0.84, 1.02] | 0.44 (0.06, 0.14, 1.39, 2.12) [0.79, 0.82] |
Legend: 1Median (Minimum, Interquartile Range, Maximum) [Mean, Standard Deviation]. Biomarker values presented represent uninfected time periods for the first five days of mechanical circulatory support. N decreases over time as patients began to develop infections. Soluble Triggering Receptor expressed on myeloid cells (sTREM-1), C-Reactive Protein (CRP). Due to the use of residual samples, there were some instances of patients missing samples.
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