Table 4
Biomarker response to infection.
Biomarker | 72 h before infection (Day-3) | 48 h before infection (Day-2) | 24 h before infection (Day-1) | Day of infection (Day 0) |
---|---|---|---|---|
N = 101 | N = 101 | N = 101 | N = 71 | |
sTREM-1 (ng/L) | 555 (174, 243, 705, 1054) [531, 305] | 524 (205, 283, 849, 1092) [576, 332] | 527 (222, 309, 557, 1174) [540, 299] | 461 (228, 413, 652, 883) [529, 231] |
Presepsin (pg/mL) | 58,166 (8476, 26,168, 117,452, 1,059,987) [161,290, 319,011] | 49,313 (9627, 27,531, 72,484, 615,634) [102,795, 181,808] | 32,334 (13,051, 21,606, 57,477, 524,715) [85,239, 155,820] | 24,080 (11,008, 17,324, 54,786, 1,004,613) [169,132, 368,893] |
CRP (mg/mL) | 131 (25, 56, 288, 1016) [251, 314] | 85 (15, 35, 305, 684) [210, 244] | 186 (9, 68, 367, 500) [219, 189] | 220 (12, 75, 304, 564) [222, 193] |
PCT (ng/mL) | 1 (0, 0, 2, 189) [20, 59] | 0 (0, 0, 1, 131) [14, 41] | 0 (0, 0, 1, 72) [8, 23] | 0 (0, 0, 1, 41) [6, 15] |
Legend: 1Median (Minimum, Interquartile Range, Maximum) [Mean, Standard Deviation]. Three patients did not have samples available for analysis on the day of infection due to the use of residual samples. 1 CRP value missing from Day-2 and Day-1. Day of infection represents the day the culture was obtained that developed an infection. Soluble Triggering Receptor expressed on Myeloid cells (sTREM-1), C-Reactive Protein (CRP).
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