Open Access

Table 8

Post-group COVID-19 subgroup analysis.

COVID-19 (n = 9) Without COVID-19 (n = 26) P-Value
Renal failure, n (%) 9 (100%) 17 (65.4%) 0.046
Time to 2 consecutive aPTTs within goal range, hours, median (IQR) 26.5 (17.7–37.9) 8.6 (3.2–14.1) 0.018
Initial dose, mg/kg/h, median (IQR) 0.05 (0.05–0.06) 0.055 (0.05–0.08) 0.426
Dose at which therapeutic aPTT achieved, mg/kg/h, median (IQR) 0.055 (0.031–0.137) 0.048 (0.032–0.086) 0.558
Number of dose adjustments until goal aPTT achieved, median (IQR) 4 (2–6) 1 (0–2) 0.017
Number of aPTT goal adjustments, median (IQR) 1 (0–1) 1 (0–1) 0.968

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