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Cited article:

Increased accuracy and precision of heparin and protamine dosing reduces blood loss and transfusion in patients undergoing primary cardiac operations

David R. Jobes, Geri Lynn Aitken and Gene W. Shaffer
The Journal of Thoracic and Cardiovascular Surgery 110 (1) 36 (1995)
https://doi.org/10.1016/S0022-5223(05)80007-8