| Issue |
J Extra Corpor Technol
Volume 16, Number 3, September 1984
|
|
|---|---|---|
| Page(s) | 77 - 82 | |
| DOI | https://doi.org/10.1051/ject/1984163077 | |
| Published online | 13 September 2023 | |
Proceedings
Alpha-Stat and pH-Stat Management Techniques in Artificial Blood Oxygenators
Extracorporeal Technologies, Inc., Indianapolis, IN
* Direct communications to: George A. Justison, 3380 Founders Road, Indianapolis, IN 46268
This clinical observation relates blood pCO2, solubility, total CO2 content, oxygenator FiCO2 and ventilation rate, CO2 transfer, and respiratory quotient during hypothermic cardiopulmonary bypass.
Techniques employed to obtain the above parameters include blood gas analysis, temperature correction, gas and blood flow settings, mass spectrometry, Kelman's algorithm of the SingerHasting nomogram, and O2 and CO2 transfer calculations.
Membrane lung O2 and CO2 transfer curves demonstrate the following respiratory quotient (RQ) and CO2 blood content requirements for two common hypothermic pCO2 management techniques:
| TECHNIQUE | COOLING | WARMING |
|---|---|---|
| pH-Stat | CO2 content increase, RQ lower than normal | CO2 content decrease, RQ much greater than normal |
| Alpha-Stat | CO2 content constant, RQ normal | CO2 content constant, RQ normal |
Oxygen, carbon dioxide transfer versus patient temperature plots from hypothermic CPB demonstrate the perfusionist's complete control of blood CO2 content and blood pCO2.
© 1984 AMSECT
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