Issue |
J Extra Corpor Technol
Volume 3, Number 2, June 1971
|
|
---|---|---|
Page(s) | 6 - 9 | |
DOI | https://doi.org/10.1051/ject/1971032006 | |
Published online | 14 November 2023 |
Original Article
Oxygen and Antipyrene Diffusion During In Vitro Human Placental Perfusion*
Departments of Pediatrics (Division of Neonatology), Obstetrics and Gynecology and the Division of Circulation Technology, School of Allied Medical Professions, The Ohio State University College of Medicine and The Children's Hospital Research Foundation, Columbus, Ohio
Using an in vitro placental perfusion apparatus, the diffusion of oxygen and antipyrene across the human placenta was studied. At varying levels of maternal pO2 there was no equilibration of fetal pO2 across the placenta. Antipyrene diffusion was relatively slow. It is suggested that this apparatus is not physiologically accurate and that any further data from these in vitro methods be accompanied by measurements of other physiological parameters.
This investigation was supported in part by funds from a Public Health Research Grant number HD 02675 from the National Institute of Child Health and Human Development by a contract with the Ohio Department of Health, Maternal and Child Health Division and from the John A. Hartford Foundation, and Public Health Service Grant number AHP-7-48-68
© 1971 AMSECT
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