Issue |
J Extra Corpor Technol
Volume 15, Number 2, April 1983
|
|
---|---|---|
Page(s) | 45 - 49 | |
DOI | https://doi.org/10.1051/ject/198315245 | |
Published online | 18 September 2023 |
Original Article
Increased Di-2-Ethyl Hexyl Phthalate (DEHP) During Extra Corporeal Circulation Using Different Oxygenators
1
Biochemistry Laboratory, Rangueil Hospital, 31054, Toulouse Cedex France
2
Cardia Vascular Surgery A and B, Rangueil Hospital, 31054, Toulouse Cedex France
Received:
20
March
1982
Revised:
16
August
1982
Accepted:
7
March
1983
The amount of Di-2-Ethyl Hexyl Phthalate (DEHP) released from the components of Extra Corporeal Circulation (ECC) systems is studied in vitro, ex vivo and in vivo experiments.
The in vitro and ex vivo studies showed that the ester is released from the Polyvinyl Chloride (PVC) used. For the in vivo study, 55 patients {vere divided into two groups. Both groups each used a different oxygenator (either a TMO or a BOS 10). Immediately after surgery a significant increase in DEHP was observed. After a 24 hours period (without ECC) the amount decreased.
A significant difference in the total phthalate ester content between the two groups revealed that the TMO patients had a higher DEHP blood level concentration than those using the BOS I 0 oxygenator.
© 1983 AMSECT
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