Issue |
J Extra Corpor Technol
Volume 21, Number 3, September 1989
|
|
---|---|---|
Page(s) | 92 - 95 | |
DOI | https://doi.org/10.1051/ject/198921392 | |
Published online | 22 August 2023 |
Literature Review/Case Report
Heparin-Induced Thrombocytopenia and Thrombosis Syndrome or H.I.T.T.S.
Departments of Cardiovascular Thoracic Surgery and Internal Medicine Oklahoma Osteopathic Hospital Tulsa, OK
* Address correspondence to: Steve P. Sanders, D.O., 5501 East 48th Place, Tulsa, OK 74135
Heparin induced thrombocytopenia has been reported to occur in 10-30% of patients receiving heparin therapy. Approximately 0.6-10% of these patients wlll develop a rare and poorly recognized paradoxical thrombosis. The suspected mechanism is an IgG mediated immune complex that causes platelet aggregation. Clinical hallmarks include thrombocytopenia, increasing heparin tolerance and recurrent arterial embolism. Laboratory testing as well as treatment modalities are presented. This paper reports on two open-heart surgery cases that developed heparin induced thrombocytopenia and the thrombosis syndrome (H.I.T.T.S.).
Key words: H.I.T.T. Syndrome / Heparin / Thrombocytopenia / Thrombosis
© 1989 AMSECT
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