Issue |
J Extra Corpor Technol
Volume 22, Number 1, March 1990
|
|
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Page(s) | 35 - 39 | |
DOI | https://doi.org/10.1051/ject/1990221035 | |
Published online | 21 August 2023 |
Technique
Effect of Oxygen Flow on pCO2 and pO2 During Cardiopulmonary Bypass in Man
Departments of Anesthesiology, Epidemiology and Biostatistics American University of Beirut, Beirut, Lebanon
* Address correspondence to: Anis Baraka, MD, Professor & Chairman, Dept. of Anesthesiology, American University of Beirut, 850 Third Ave., 18th Floor, New York, NY 10022.
The effect of oxygen flow on arterial pO2 and pCO2 was investigated during cardiopulmonary bypass in three groups of patients undergoing open heart surgery. A Bentley-10 adult bubble oxygenator was used in all patients. The perfusion was maintained in the three groups at a constant flow of 2.31/m2/min throughout bypass. The oxygenator was bubbled in Group 1 by oxygen at an oxygen:perfusion ratio of 0.75:1.0 while 1.0:1.0 ratio was used in Group 2 and 1.5:1.0 ratio was used in Group 3. After going on bypass, moderate hypothermia was achieved, and the patients were rewarmed when surgery was completed.
The report shows that the arterial pCO2, and pO2 may be determined during cardiopulmonary bypass by the bubbled oxygen flow. Increasing the oxygen:perfusion ratio from 0.5:1.0 to 1.0: 1.0 is associated with a significant decrease of pCO2 and increase of pO2. Further increase of the oxygen:perfusion ratio to 1.5:1.0 resulted in further decrease of pCO2 without a significant increase of pO2. The results suggest that optimal oxygenation and carbon dioxide elimination can be achieved by using an oxygen:perfusion ratio 1.0:1.0 during hypothermia and following rewarming.
Key words: Cardiopulmonary bypass / bubble oxygenator / acid-base balance / alpha-stat / pCO2 / pH / oxygenation / pO2
© 1990 AMSECT
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