Issue |
J Extra Corpor Technol
Volume 23, Number 4, December 1991
|
|
---|---|---|
Page(s) | 76 - 79 | |
DOI | https://doi.org/10.1051/ject/199123476 | |
Published online | 21 August 2023 |
Lecture
Cerebral Blood Flow During Cardiopulmonary Bypass*
Associate Professor of Anaesthesia, Department of Anaesthesia, University Hospital University of Western Ontario, Ontario, London
* AddresscCorrespondence to: Dr. John M. Murkin, Department of Anaesthesia University Hospital 339 Windermere Road London, Ontario, N6A 5A5
This article reviews the development of cerebral blood flow techniques as used both clinically and experimentally formeasurementofcerebralbloodflow(CBF)andcerebral metabolic rate for oxygen (CMRO2) during cardiopulmonary bypass (CPB). The limitations associated with the various techniques for measurement of CBF during cardiopulmonary bypass are discussed, as well as considering the influence of some of the management options, including pH management and use of pulsatile or non pulsatile perfusion, on CBF and CMRO2 The impact of various perfusion techniques on neurological outcome following cardiopulmonary bypass is also considered.
Key words: cerebral blood flow / cardiopulmonary bypass / cerebral metabolism / acid-base balance / pulsatile flow / normothermia / microemboli
© 1991 AMSECT
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