Issue |
J Extra Corpor Technol
Volume 25, Number 2, June 1993
|
|
---|---|---|
Page(s) | 67 - 70 | |
DOI | https://doi.org/10.1051/ject/1993252067 | |
Published online | 21 August 2023 |
Case Report
Damaged Erythrocytes Following Cell Washing with a Hypotonic Solution: A Case Report
Division of Clinical Perfusion Sciences, School of Allied Health Professions, University of Nebraska Medical Center
* Address correspondence to: Allen Hunt, BS, RN Division of Clinical Perfusion Sciences School of Allied Health Professions University of Nebraska Medical Center 600 S. 42nd Street Omaha, Nebraska 68198-5150
This case report deals with the incidence of high levels of plasma free hemoglobin secondary to the infusion of erythrocytes washed with sterile water during an autotransfusion procedure. The danger of high levels of plasma free hemoglobin is acute renal failure due to precipitation of free hemoglobin in the form of acid hematin. Treatment attempts to prevent the precipitation by maintaining high urine output (75 - 100 ml/hr or 1-2 ml/kg/min) and alkalizing the urine (pH of8). Preventative treatment is outlined and includes: fluid and colloid replacement; diuretics and sodium bicarbonate. In this case, acute renal failure was prevented and the patient was discharged on post operative day five.
Key words: cardiopulmonary bypass / autotransfusion / hemoglobinuria / hemolytic transfusion reaction
© 1993 AMSECT
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