Technique Article

A Technique for Autologous Priming of the Veno-Venous Bypass Circuit during Liver Transplantation

^* Division of Cardiovascular Perfusion, College of Health Professions, Medical University of South Carolina, Charleston, South Carolina
^† Department of Surgery, College of Medicine, Medical University of South Carolina, Charleston, South Carolina

Address correspondence to: Anthony G. Shackelford, Assistant Professor/Perfusionist, Division of Cardiovascular Perfusion, Medical University of South Carolina, 151 Rutledge Avenue, Building B, MSC962, Charleston, SC 19425. E-mail: shackela@musc.edu

Received: 29 December 2010
Accepted: 2 May 2011

Abstract

Orthotopic liver transplantations (OLT) have been associated with significant blood loss and hemodilution, necessitating significant homologous blood component replacement. Increasing administration of homologous blood products has been found to be inversely related to patient and graft survival. Various methods to reduce the amount of blood products patients receive during OLT, such as antifibrinolytic therapy, thromboelastography-guided transfusion, phlebotomy, reduced central venous pressures intraoperatively, and the use of the veno-venous bypass (VVB) circuit, have been explored. The asanguineous priming volume of the VVB circuit increases the likelihood of the patient receiving homologous blood products due to hemodilution. It was reasoned that autologous priming of the VVB circuit in OLT surgery was a plausible adjunctive blood conservation technique given its application to the extracorporeal circuit during cardiac surgery. We describe our technique of modifying the VVB circuit for autologous priming. This technique adds minimal risk and a small amount of cost to the procedure, requires slightly more communication among members of the surgical team, and with proper sequencing, adds no additional length to the surgical procedure. It is recommended that this technique be considered for addition to the arsenal of blood conservation techniques when VVB is used during OLT.