Issue |
J Extra Corpor Technol
Volume 46, Number 4, December 2014
|
|
---|---|---|
Page(s) | 314 - 316 | |
DOI | https://doi.org/10.1051/ject/201446314 | |
Published online | 15 December 2014 |
Case Reports
Failure of Intraoperative Red Cell Salvage: A Patient with Sickle Cell Disease and HELLP (Hemolysis, Elevated Liver enzymes and Low Platelets) Syndrome
* Departments of Anesthesiology, Pittsburgh, Pennsylvania
† Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Address correspondence to: Jonathan H. Waters, MD, Chief and Professor, Department of Anesthesiology, Magee Women’s Hospital of Pittsburgh of UPMC, 300 Halkett Street, 3rd Floor, Room 3510, Pittsburgh, PA 15213. E-mail: watejh@upmc.edu
Received:
17
August
2014
Accepted:
15
November
2014
Cell salvage is a process whereby the bloodshed from the operative field is collected and returned to the patient. It can be especially useful when allogeneic red blood cell (RBC) units are not readily available such as when the recipient has multiple alloantibodies. We report on the anesthesia and transfusion strategies for managing a pregnant patient with sickle cell disease (SCD) with HELLP (Hemolysis, Elevated Liver enzymes and Low Platelets) syndrome. A pregnant patient with twins at 30 weeks of gestation was admitted in an SCD crisis. She subsequently developed HELLP syndrome and required urgent cesarean delivery; however, she had multiple RBC antibodies complicating the immediate provision of crossmatched RBC units. Cell salvage was used to capture the blood shed during her procedure while the blood bank was searching for compatible RBCs units. Despite multiple interventions designed to optimize the cell salvage procedure for the unique challenges of a patient with SCD, the salvaged RBCs hemolyzed and could not be reinfused. Cell salvage in an obstetric patient with SCD in an acute crisis and superimposed HELLP was unable to recover intact and useable RBCs. Further studies into methods of optimizing the procedure for use in this context are warranted. Close communication between the clinical teams treating the patient and the transfusion service is required so that the RBC transfusion requirements can be anticipated; this is especially important when the patient has multiple antibodies.
Key words: sickle cell disease / HELLP syndrome / cell salvage / thromboelastogram / anticoagulation
© 2014 AMSECT
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