Issue |
J Extra Corpor Technol
Volume 55, Number 2, June 2023
|
|
---|---|---|
Page(s) | 94 - 97 | |
DOI | https://doi.org/10.1051/ject/2023009 | |
Published online | 28 June 2023 |
Case Report
ABO-incompatible orthotopic heart transplant: a case report★
Medical University of South Carolina, 171 Ashley Ave, Charleston 29425, USA
* Corresponding author: chiarel@musc.edu
Received:
16
September
2021
Accepted:
9
March
2023
Background: ABOi heart transplant has become routine for the majority of children <2 years old. An 8-month-old child with complex congenital heart disease presented to the Medical University of South Carolina Shawn Jenkins Children’s Hospital in need of transplantation. Methods: This case report describes the use of ABOi transplantation and describes the details of the total exchange transfusion prior to cardiopulmonary bypass. Results: After a successful intraoperative total exchange transfusion following the ABOi protocol, the patient’s isohemagglutinin titers were 1 VC on postoperative day (POD) 1, and isohemagglutinin titer was <1 VC on POD 14. The patient had no signs of rejection and continued to recover. Conclusions: Successful ABOi transplantation requires planning, an interdisciplinary approach, and clear closed-loop communication. Planning with the surgical and anesthesia teams is necessary for the hemodynamic stability of the patient during the total volume exchange as well as precautions put in place to ensure the blood products used in this procedure are correct. Planning with the lab and blood bank is also necessary to ensure they are prepared with enough blood products and can run isohemagglutinin titers.
Key words: ABO-incompatible (ABOi) / Heart transplantation / Pediatric / Congenital heart disease / Cardiopulmonary bypass / Exchange transfusion / Antibodies
This case report was presented as a scientific poster at the Carolina Perfusion Symposium in Myrtle Beach, SC July 30th to August 1st, 2021, and as an oral presentation at the virtual 23rd Annual Update on Perfusion Conference sponsored by the Medical University of South Carolina Cardiovascular Perfusion program on October 30th, 2021.
© The Author(s), published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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