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Table 2
Heparin rate adjustments for maintenance infusion protocol.
| Start infusion at 15 units/kg/h (max 1800 units/h) |
||||
|---|---|---|---|---|
| Goal aPTT (44–66, 67–92): | ||||
| 44–66 | 67–92 | Bolus dose | Change current infusion | Order next PTT |
| <23 | <47 | Give maintenance bolus dose | Increase rate by 4 units/kg/h | 4 h |
| 23–43 | 47–66 | None | Increase rate by 2 units/kg/h | 4 h |
| 44–66 | 67–92 | None | Goal range, continue current rate | 4 h × 1, then every AM |
| 67–92 | 93–107 | None | HOLD for 30 min, then decrease rate by 2 units/kg/h | 4 h |
| 93–107 | 108–126 | None | HOLD for 1 h, then decrease rate by 3 units/kg/h | 4 h after start of infusion |
| >107 | >126 | None | HOLD for 2 h, then decrease rate by 4 units/kg/h | 4 h after start of infusion |
**If PTT > 120 for two consecutive PTT values and/or > 200 for any PTT result, HOLD infusion and notify Physician**.
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