The percent of time with COx > 0.40 or COx < −0.40 in each subject (red dots) related to results based on a unique mixture of 90 uncorrelated signals including all subjects’ individual rSO₂ signals and a combination of MAP signals from the remaining cases. The 5–95% interval is indicated by the shaded area and the median and quartiles with solid and dashed lines. The red dots represent the results based on the recorded signals in each subject. Two subjects presented more frequent COx > 0.40 than expected by the 95% interval for uncorrelated signals.