Comparison of routine del Nido cardioplegia vs two types of modified del Nido cardioplegias for myocardial protection among patients undergoing coronary artery bypass grafting (CABG) surgeries: A randomized double-blind clinical trial

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Table 3

Intraoperative and postoperative clinical characteristics.

	Control group (rdNC)	Group A (rldNCS)	Group B (prdNCS)	p-value
	n = 40	n = 40	n = 40	p-value
Bypass time (min)	68.5 (60–80)	68.5 (60–86.75)	70 (65–75.75)	0.824
Clamp time (min)	42.5 (35.75–47.75)	41.5 (38.25–54.75)	44.5 (38–49.25)	0.796
Post clamp off VF. DC	14 (35)	11 (27.3)	12 (30)	0.761
Total grafts	4 (3.25–4)	4 (4–4)	4 (3–4)	0.536
CK-MB (U·L⁻¹)
Baseline	12.22 ± 7.26	10.35 ± 7.18	12.82 ± 6.71	Time = 0.344
2 h	13.22 ± 7.09	11.52 ± 7.17	15.30 ± 7.10	Time × Gp = 0.787
12 h	12.05 ± 7.27	11.81 ± 7.29	12.90 ± 7.59	Group = 0.078
24 h	12.61 ± 6.83	11.86 ± 7.32	12.37 ± 7.03
Trop T (ng·mL⁻¹)
Baseline	0.106 ± 0.055	0.108 ± 0.060	0.105 ± 0.063	Time = 0.034^*
2 h	0.128 ± 0.067	0.132 ± 0.060	0.119 ± 0.063	Time × Gp = 0.759
12 h	0.115 ± 0.066	0.133 ± 0.074	0.130 ± 0.066	Group = 0.143
24 h	0.107 ± 0.076	0.126 ± 0.077	0.095 ± 0.069
Trop I (ng·mL⁻¹)
Baseline	0.016 ± 0.009	0.020 ± 0.016	0.012 ± 0.012	Time = 0.609
2 h	0.015 ± 0.011	0.019 ± 0.015	0.014 ± 0.014	Time × Gp = 0.444
12 h	0.018 ± 0.009	0.020 ± 0.009	0.015 ± 0.014	Group = 0.311
24 h	0.019 ± 0.010	0.017 ± 0.010	0.015 ± 0.015
Lactate (mg·dL⁻¹)
Baseline	10.42 ± 5.10	11.73 ± 4.89	11.38 ± 4.95	Time = <0.001^*
2 h	14.65 ± 6.11	14.03 ± 5.27	12.52 ± 4.60	Time × Gp = 0.064
12 h	15.54 ± 5.61	12.08 ± 5.07	13.30 ± 4.67	Group = 0.129
24 h	12.11 ± 4.30	11.65 ± 4.07	11.15 ± 4.02
Post operative AFL	2 (5)	3 (7.5)	4 (10)	0.908
Post operative AF	4 (10)	5 (12.5)	4 (10)	>0.999
Ventilation support (h)	5.7 (4.5–6.5)	5.5 (4.1–6.5)	5.7 (4.5–7)	0.580
ICU stay (h)	64 (43.23–85.25)	63.5 (40.50–75.75)	52 (45.50–69.50)	0.484

CK-MB (Creatine Kinase-Myoglobin Binding), Trop T (Troponin T), Trop I (Troponin I), VF. DC (Ventricular Fibrillation needing Direct Current Cardioversion), AFL (Atrial Flutter), AF (Atrial Fibrillation), ICU (Intensive Care Unit).

p < 0.05.

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