Open Access
Table 1
Summary of patient demographic. TXA = Tranexamic Acid, CABG = coronary artery bypass grafting, CPB = cardiopulmonary bypass, AOX = aortic cross clamp.
| All patients (n = 5521) | CAM-ICU negative (n = 4519, 82%) | CAM-ICU positive (n = 1002, 18%) | p-value | |
|---|---|---|---|---|
| TXA (mg/kg) | 24.1 [24.1–24.39] | 24.1 [20.8–27.8] | 24.7 [21.1–28.6] | 0.07 |
| Age | 71 [71–71] | 70 [62–76] | 73 [66–78] | <0.001 |
| Sex | ||||
| Male | 4013 | 3319 (83%) | 694 (17%) | |
| Female | 1508 | 1200 (80%) | 308 (20%) | |
| Left ventricular function | ||||
| Good | 3691 | 3099 (84%) | 592 (16%) | |
| Moderate | 1517 | 1199 (79%) | 318 (21%) | |
| Poor | 217 | 155 (71%) | 62 (29%) | |
| Very poor | 96 | 66 (69%) | 30 (31%) | |
| Hypertension | ||||
| Yes | 2998 | 2422 (81%) | 576 (19%) | |
| No | 2523 | 2097 (83%) | 426 (17%) | |
| Diabetes mellitus | ||||
| Yes | 1618 | 1270 (78%) | 348 (22%) | |
| No | 3903 | 3249 (83%) | 654 (17%) | |
| Previous stroke | ||||
| Yes | 324 | 241 (74%) | 83 (26%) | |
| No | 5197 | 4278 (82%) | 919 (18%) | |
| Operation type | ||||
| Aorta | 198 | 167 (84%) | 31 (16%) | |
| CABG | 2117 | 1804 (85%) | 313 (15%) | |
| CABG + other | 1074 | 764 (71%) | 310 (29%) | |
| Valve | 1683 | 1421 (81%) | 262 (16%) | |
| Valve + other | 370 | 299 (81%) | 71 (19%) | |
| Other | 79 | 64 (81%) | 15 (195) | |
| EuroSCORE 2 | 1.83 [1.78–1.87] | 1.7 [1.0–3.1] | 2.9 [1.6–6.3] | <0.001 |
| CPB (min) | 98 [97–99] | 95 [75–122] | 114 [88–151] | <0.001 |
| AOX (min) | 65 [64–66] | 63 [49–84] | 76 [55–105] | <0.001 |
| ICU LOS (d) | 1.2 [1.2–1.2] | 1.2 [1.1–1.9] | 3.3 [1.4–7.5] | <0.001 |
| Hospital LOS (d) | 9.11 [9.02–9.19] | 8.3 [6.4–12.7] | 13.1 [8.9–20.9] | <0.001 |
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