Proceedings

A Computer Simulation of Cardiopulmonary Bypass: Version Two

Extracorporeal Technologies, Inc., Indianapolis, IN

^* Direct Communications to: Jeffrey B. Riley, 3380 Founders Road, Indianapolis, IN 46268

Abstract

The second and more complete version of a computer simulation of CPB is presented. Version Two simulates oxygen transfer, carbon dioxide transfer, and heat transfer.

BASIC computer statements were created to mimic the clinical function of the hollow fiber membrane oxygenator. The oxygenator function curves were created from over 400 clinical oxygenation and carbon dioxide measurements from four institutions. Heat transfer and normal physiological relationships were simultated in computer statements written from well-documented sources. The educational computer program reproduces each step of the heat, oxygen, and carbon dioxide transfer, as well as acid/base and vasomotor status change. The input parameters for the simulation are blood flow, Fi02, FiC02, gas sweep rate, mean arterial pressure, hematocrit, and water temperature and are introduced into the computer with control rheostats.

Version Two simulates pathophysiologic events and the effect of an individual control parameter. The simulation provides a cost effective means of providing vital information for medical, allied health, and industrial training and product design.