Issue |
J Extra Corpor Technol
Volume 21, 1989
Proceedings of AmSECT’s 27th International Conference
|
|
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Page(s) | 24 - 29 | |
DOI | https://doi.org/10.1051/ject/198921S024 | |
Published online | 24 August 2023 |
Original Article
The Effect of Gas Scavenging on Hollow Fiber Membrane Oxygenator Performance
Providence Medical Center, Portland, OR
* Address correspondence to: Charles F. Jerabek, Department of Surgery, Providence Medical Center, 4805 N. E. Glisan, Portland, OR 97213
During a routine cardiopulmonary bypass a patient's blood gases did not respond in the expected manner. After detailed review it was determined that the gas scavenging system was affecting the hollow fiber membrane oxygenator's performance, even though it was set up according to manufacturer's recommendations. Using a closed oxygenator-deoxygenator system primed with recently outdated human blood, the hypothesis that changing gas scavenging suction levels affected oxygenator performance was tested. Pump speed, venous blood gas levels, temperature, hemoglobin, FIO2 and sweep gas rate were all kept constant. The results showed that as suction levels increased, oxygenation capacity decreased according to the formula:
Suction(mm.Hg)=5130 * .98^ (Art. PO2 - Venous PO2) [R=-1].
However, ventilation capacity increased following the equation:
Suction(mm.Hg)=-945.26 + 65.67*(Venous PCO2-Art. PCO2) [R=.78].
Sweep gas flow rate was 2.5 liters/minute and FIO2 was 50%. Results were comparable when a different FI02 was used as a baseline. The conclusion was that gas scavenging suction predictably affects hollow fiber membrane oxygenator performance and can be used as an adjunct in blood gas management. However, if a perfusionist wishes to minimize the effects of gas scavenging, then a regulated low pressure vacuum source must be used.
Key words: Oxygenator / membrane / gas scavenging / oxygenator peformance / FiO2
© 1989 AMSECT
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