| Issue |
J Extra Corpor Technol
Volume 22, 1990
Proceedings of AmSECT’s 28th International Conference
|
|
|---|---|---|
| Page(s) | 68 - 71 | |
| DOI | https://doi.org/10.1051/ject/199022S068 | |
| Published online | 23 August 2023 | |
Original Article
A Convertible Cardiopulmonary Bypass System for Optimized Hemofiltration
Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland
* Address correspondence to: Ludwig K. von Segesser, M.D, Clinic for Cardiovascular Surgery, University Hospital, CH-8091 Zurich, Switzerland.
Hemofiltration during or after cardiopulmonary bypass has proved to be an efficient tool for hemoconcentration. Classically, the hemofilters are supplied by the arterial line and the filtration rate is mainly a function of the perfusion pressure. We have developed a convertible cardiopulmonary bypass system including a double head roller pump for blood cardioplegia application that allows optimized hemofiltration independent from systemic perfusion. Serial bench studies were performed at normothermia with a mean hematocrit of 20%, and identical hemofilters:
| CLASSIC | OPTIMIZED | p< | |
| Systemic pump flow 1/min | 3.5±0.9 | 3.5±0±.9 | NS |
| Arterial line pressure mmHg | 148±3 | 135±8 | 0.05 |
| Filter line pressure mmHg | 144±8 | 378±30 | 0.05 |
| Filter flow ml/min | 152±3 | 346±6 | 0.05 |
| Filter output ml/15 min | 999±228 | 1599±174 | 0.05 |
Hemofiltration can be optimized by a convertible cardiopulmonary bypass system allowing independent hemofilter-flow adjustment. Improved results were confirmed in routine clinical application.
Key words: Cardiopulmonary bypass / hemofiltration / hemoconcentration
© 1990 AMSECT
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