Abstract

Blood Component Therapy in Trauma Guided with the Utilization of the Perfusionist and Thromboelastography

^* Memorial Hospital, South Bend, Indiana
^† Vanderbilt University School of Medicine, Nashville, Tennessee
^‡ Indiana University School of Medicine, South Bend Campus, South Bend, Indiana
^§ W.M. Keck Transgene Center, University of Notre Dame, Notre Dame, Indiana

Address correspondence to: Mark Walsh, MD, Director of Medical Education, Emergency Department, Memorial Hospital, 615 North Michigan Avenue, South Bend, Indiana 46601. E-mail: markwalshmd@gmail.com

Received: 3 September 2010
Accepted: 25 January 2011

Abstract

25–35% of all seriously injured multiple trauma patients are coagulopathic upon arrival to the emergency department, and therefore early diagnosis and intervention on this subset of patients is important. In addition to standard plasma based tests of coagulation, the thromboelastogram (TEG®) has resurfaced as an ideal test in the trauma population to help guide the clinician in the administration of blood components in a goal directed fashion. We describe how thromboelastographic analysis is used to assist in the management of trauma patients with coagulopathies presenting to the emergency department, in surgery, and in the postoperative period. Indications for the utilization of the TEG® and platelet mapping as point of care testing that can guide blood component therapy in a goal directed fashion in the trauma population are presented with emphasis on the more common reasons such as massive transfusion protocol, the management of traumatic brain injury with bleeding, the diagnosis and management of trauma in patients on platelet antagonists, the utilization of recombinant FVIIa, and the management of coagulopathy in terminal trauma patients in preparation for organ donation. The TEG® allows for judicious and protocol assisted utilization of blood components in a setting that has recently gained acceptance. In our program, the inclusion of the perfusionist with expertise in performing and interpreting TEG® analysis allows the multidisciplinary trauma team to more effectively manage blood products and resuscitation in this population.