Issue |
J Extra Corpor Technol
Volume 44, Number 2, June 2012
|
|
---|---|---|
Page(s) | 60 - 65 | |
DOI | https://doi.org/10.1051/ject/201244060 | |
Published online | 15 June 2012 |
Technique Article
Modification of Sodium, Glucose, Potassium, and Osmolarity in Packed Red Blood Cells and Fresh Frozen Plasma Using a Desktop Hemoconcentrator Setup
* Children’s Mercy Hospitals and Clinics, Kansas City, Missouri
† University of Nebraska Medical Center, Omaha, Nebraska
Address correspondence to: Carrie Whittaker Striker, DHEd, CCP, FFP, Pediatric Perfusionist, Department of Cardiothoracic Surgery, Children’s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108. E-mail: clstriker@cmh.edu
Received:
8
April
2010
Accepted:
18
April
2012
Massive transfusion with packed blood cells (PRBCs) or fresh frozen plasma (FFP) can result in dangerous complications including stroke, kidney failure, and cardiac arrest. A simple, bench top technique using a hemoconcentrator and dialysate solution is described to correct critical values of sodium, glucose, potassium, and osmolarity in PRBCs and FFP. Sodium, glucose, and osmolarity were corrected to normal or near normal values. Elevated potassium was reduced by 65%, but not completely normalized. A simple, bench top method for correcting dangerous abnormalities with PRBCs and FFP can be used to improve the safety of massive blood transfusion.
Key words: hemoconcentrator / dialysis / dialyzed PRBCs / dialyzed FFP / osmolarity / sodium / glucose / potassium / hyperosmolarity / hypernatremia / hyperglycemia / washed blood products
© 2012 AMSECT
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