Issue |
J Extra Corpor Technol
Volume 47, Number 1, March 2015
|
|
---|---|---|
Page(s) | 38 - 43 | |
DOI | https://doi.org/10.1051/ject/201547038 | |
Published online | 15 March 2015 |
Original Articles
Performance and Safety of an Integrated Portable Extracorporeal Life Support System for Adults
* Cardiothoracic Surgery Division, Department of Surgery, Mayo Clinic Hospital, Phoenix, Arizona
† Department of Nursing, Mayo Clinic Hospital, Phoenix, Arizona
Address correspondence to: Cory M. Alwardt, PhD, CCP, Chief Perfusionist, Division of Cardiothoracic Surgery, Mayo Clinic Hospital, 5777 E Mayo Blvd., Phoenix, AZ 85054. E-mail: alwardt.cory@mayo.edu
Received:
8
October
2014
Accepted:
10
February
2015
Extracorporeal membrane oxygenation (ECMO) is indicated when conventional measures fail to support a patient during cardiac or respiratory failure. Due to the complicated nature of ECMO, patients often require transport to a tertiary care center. This study retrospectively compared the performance of the Cardiohelp™ (Maquet) life support system with a previously used ECMO circuit when transporting adult patients on venoarterial ECMO between facilities. Two ECMO circuits were compared for performance: 1) the Cardiohelp™ (Maquet) life support system and 2) the “standard” circuit consisting of a Thoratec CentriMag centrifugal pump, Maquet Quadrox-D oxygenator, and a Terumo CDI-500 in-line blood gas analyzer. After analyzing data from 16 patients (eight patients supported with each ECMO system), no differences in patient demographics, percentage of patients successfully weaned from ECMO, percentage of patients surviving to discharge, duration supported on the initial ECMO system, or total duration of ECMO were noted. No patient deaths were related to circuit failure or circuit disruptions in either group. Analysis of the performance of the ECMO circuits and the resulting patient status showed few significant differences between ECMO groups (Cardiohelp™ vs. standard circuit) and time points (the first 8 hours vs. a 24-hour time point). The statistically significant differences were not concerning in terms of appropriate medical support or patient safety. Of interest, the transmembrane pressure was significantly lower for the Cardiohelp™ module vs. the standard oxygenator during the first 8 hours (20.1 [5.3] vs. 37.1 [7.1] mmHg; p < .001) and at 24 hours (21.3 [3.8] vs. 34.8 [7.9] mmHg; p = .001). The Cardiohelp™ portable life support system provides safe and reliable support for adult patients on ECMO during interhospital patient transport as compared to the standard circuit.
Key words: ECMO / extracorporeal / extra corporeal life support / extracorporeal membrane oxygenation / transport
© 2015 AMSECT
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