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Table 1

Demographics and preoperative characteristics by AKI for STAT 4 & 5 neonates (n = 463) and STAT 1–3 infants (n = 517).

All (n = 980) Non-AKI (n = 768) AKI (n = 212) p value
Frequency (%)
Age at surgery
 <31 days 463 (47.2) 336 (43.8) 127 (59.9) <0.001
 31 days – ≤1 year 517 (52.8) 432 (56.3) 85 (40.1)
Male 550 (56.1) 421 (54.8) 129 (60.9) 0.11
Race 0.07
 White 536 (54.7) 420 (54.7) 116 (54.7)
 Black 134 (13.7) 114 (14.8) 20 (9.4)
 Other 310 (31.6) 234 (30.5) 76 (35.9)
Hispanic or Latino 165 (16.8) 122 (15.9) 43 (20.3) 0.12
Gestational age < 37 weeks 132 (13.7) 99 (13.1) 33 (15.9) 0.29
Ventricular physiology 0.24
 Single ventricle 364 (37.1) 278 (36.2) 86 (40.6)
 Two ventricles 616 (62.9) 490 (63.8) 126 (59.4)
Max STAT score <0.001
 1 191 (19.5) 172 (22.4) 19 (9)
 2 211 (21.5) 171 (22.3) 40 (18.9)
 3 115 (11.7) 89 (11.6) 26 (12.3)
 4 296 (30.2) 227 (29.6) 69 (32.6)
 5 167 (17) 109 (14.2) 58 (27.4)
STS risk factors
 Chromosomal anomaly 328 (33.5) 260 (33.9) 68 (32.1) 0.62
 Preoperative mechanical ventilation 130 (13.3) 82 (10.7) 48 (22.6) <0.001
 Emergency 2 (0.2) 1 (0.1) 1 (0.5) 0.38
 Cardiopulmonary Resuscitation 7 (0.7) 7 (0.9) 2 (0.9) 0.35
 Colostomy 8 (0.8) 6 (0.8) 1 (0.5) 0.68
 Endocarditis 2 (0.2) 1 (0.1) 10 (4.7) 0.38
 Gastrostomy 34 (3.5) 24 (3.1) 2 (0.9) 0.26
 Necrotizing enterocolitis treated medically 11 (1.1) 9 (1.2) 2 (0.9) 1.00
 Atrioventricular block 6 (0.6) 4 (0.5) 2 (0.9) 0.61
 Mechanical circulatory support 4 (0.4) 2 (0.3) 1 (0.5) 0.20
 Renal dysfunction 3 (0.3) 2 (0.3) 5 (2.4) 0.51
 Seizure 27 (2.8) 22 (2.9) 3 (1.4) 0.69
 Sepsis 8 (0.8) 5 (0.7) 1 (0.5) 0.38
 Shocking occurring at reoperation 3 (0.3) 2 (0.3) 9 (4.3) 0.51
 Shock resolved at time of operation 21 (2.1) 12 (1.6) 16 (7.6) 0.02
 Stroke 51 (5.2) 35 (4.6) 68 (32.1) 0.08
Mean (SD)
 Age at surgery in years 0.0 (0.5) 0.0 (0.1) 0.1 (1.0) 0.34
 Weight at surgery in kg 4.4 (2.0) 4.4 (1.5) 4.2 (3.3) 0.58
 BSA at surgery in m2 0.3 (0.1) 0.3 (0.1) 0.3 (0.1) 0.12
 Gestational age 38.0 (2.2) 38.0 (2.1) 37.7 (2.3) 0.07
 Preoperative creatinine in mg/dL 0.4 (0.4) 0.4 (0.5) 0.4 (0.2) 0.93
 Total number of 16 STS preoperative risk factors 0.7 (0.9) 0.6 (0.8) 0.8 (1.0) 0.01

Variables were compared using t-test, χ2 test, and Fisher’s exact test. Data is presented as mean (standard deviation) or as number (percent). BSA: body surface area; SD: standard deviation; STAT: Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery; STS: Society of Thoracic Surgeons.

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