Table 2
Operative characteristics by AKI for STAT 4 & 5 neonates (n = 463) and STAT 1–3 infants (n = 517).
| All (n = 980) | Non-AKI (n = 768) | AKI (n = 212) | p value | |
|---|---|---|---|---|
| CPB time (min) | 70.0 (41.0) | 67.0 (42.0) | 84.0 (45.5) | <0.001 |
| Cross clamp time (min) | 37.0 (33.0) | 34.0 (32.0) | 50.0 (39.0) | <0.001 |
| Use of DHCA | 562 (42.7) | 307 (40.0) | 111 (52.4) | <0.001 |
| Nadir NP temperature (°C) | 34.0 (7.1) | 34.0 (7.0) | 33.0 (15.0) | <0.001 |
| Nadir hematocrit | 25.0 (4.0) | 25.0 (4.0) | 25.0 (4.0) | 0.03 |
| CPB cardiac index (L/min/m2) | 2.5 (0.4) | 2.5 (0.4) | 2.5 (0.5) | 0.03 |
| Median VO2 (mL/min/m2) | 72.3 (60.8) | 77.3 (61.3) | 57.7 (58.5) | <0.001 |
| Median SvO2 (%) | 78.0 (16.5) | 77 (16) | 81 (16) | <0.001 |
| Median PO2 (mmHg) | 289.0 (49.5) | 289 (48.9) | 290 (54.5) | 0.34 |
| Median oxygen extraction ratio | 20.5 (16.1) | 21.5 (15.6) | 16.8 (15.5) | <0.001 |
| Intraoperative transfusion (y/n) | 754 (76.9) | 572 (74.5) | 182 (85.9) | <0.001 |
| Whole blood (mL/kg) | 0 (8.8) | 6.9 (18.8) | 11.6 (26) | 0.001 |
| RBC (mL/kg) | 0 (0) | 0 (4.9) | 0 (23.5) | <0.001 |
| FFP (mL/kg) | 0 (0) | 0 (0) | 0 (0) | <0.001 |
| Platelets (mL/kg) | 0 (0) | 0 (0) | 0 (8.3) | 0.003 |
| Use of modified ultrafiltration | 949 (96.8) | 744 (96.9) | 205 (96.7) | 0.97 |
| Total UF volume (mL/kg) | 90.9 (47.6) | 88.5 (45.4) | 99.4 (56.2) | <0.001 |
| Total UF volume ≥ 119.9 mL/kg | 223 (22.8) | 150 (19.6) | 73 (34.4) | 0.001 |
| AUC < DO2i400 | 1978.5 (2651.5) | 1882.8 (2483) | 2533.7 (3858.6) | <0.001 |
| AUC < DO2i380 | 1363.3 (2085.5) | 1308.1 (1941.7) | 1854.6 (3091.1) | <0.001 |
| AUC < DO2i360 | 933.1 (1541.4) | 884.7 (1390) | 1210.8 (2266.5) | <0.001 |
| AUC < DO2i340 | 634.7 (1008.3) | 585.4 (923.9) | 796.1 (1521.6) | <0.001 |
| AUC < DO2i320 | 411.2 (711.6) | 378.1 (645.4) | 564.4 (981.3) | <0.001 |
| AUC < DO2i300 | 283.5 (497.9) | 274.5 (472) | 353.3 (633.5) | <0.001 |
| AUC < DO2i280 | 223.7 (398.9) | 213.9 (357.6) | 258.4 (452.3) | 0.003 |
| AUC < DO2i260 | 167.6 (320.7) | 158.3 (299) | 198.2 (424.2) | 0.01 |
Variables were compared using the Mann–Whitney U test or χ2 test. Data are presented as median (IQR) because of non-normal distribution or as number (percent). AUC: area under the curve; CPB: cardiopulmonary bypass; DHCA: deep hypothermic circulatory arrest; DO2i: indexed oxygen delivery; FFP: fresh frozen plasma; NP: nasopharyngeal; PO2: partial pressure of oxygen; RBC: red blood cells; SvO2: venous oxygen saturation; UF: ultrafiltration; VO2: oxygen consumption.
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