Case example: (A) MAP (grey curve), rSO₂ (blue curve) and the COx index (red curve) from initiation of cardiopulmonary bypass until weaning (49 min). (B) The MAP sorted from low to high based on the mean value over 2.5-minute intervals (grey curve). The red curve represents the corresponding trended average COx value including 20 registrations. Reference line COx = 0.4 (green dotted line).