Open Access
Table 5
Integration of temperature, DO2, and CO2 management threshold example.
| Temperature (°C) | pH strategy | DO2 optimization | CO2 strategy |
|---|---|---|---|
| 37 °C | Alpha-stat | High flow, normothermia | Standard CO2 removal |
| 32 °C | Alpha-stat | Moderate-flow, reduced VO2 | Moderate CO2 removal |
| 28 °C | Alpha-stat or pH-stat | Lower flow, adjusted DO2 | Adjusted CO2 sweep |
| 22 °C | pH-stat | Minimal flow to match metabolism | High CO2 sweep to maintain pH |
| 18 °C | pH-stat | Low-flow or arrest | Max CO2 sweep to prevent acidosis |
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