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Table E

The Modified SAVE score parameters and assigned scores [29].

Parameter Score
Acute cardiogenic shock diagnosis group (select one or more)
– Myocarditis
– Refractory VT/VF
– Post heart or lung transplant
– Congenital heart disease
– Other diagnoses leading to cardiogenic shock
3
2
3
−3
0
Age (years)
– 18–38
– 39–52
– 53–62
– ≥63
7
4
3
0
Weight (kg)
– ≤65
– 65–89
– ≥90
1
2
0
Acute pre-ECMO organ failures
– Liver failure (bilirubin ≥33 umol/L or ALT/AST >70 UI/L)
Central nervous system (CNS) dysfunction (neurotrauma, stroke, encephalopathy, cerebral embolism, seizure/epileptic syndromes)
– Renal failure (acute renal insufficiency: creatinine >1.5 mg/dL with or without RRT)
– Chronic renal failure (kidney damage or GFR <60 mL/min/1.73 m2 for ≥3 mos.)
−3
−3
−3
−6
Duration of intubation before initiation of ECMO (hrs)
– ≤10
– 11–29
– ≥30
0
−2
−4
Peak inspiratory pressure ≤ 20 cm H2O 3
Pre-ECMO cardiac arrest −2
Diastolic blood pressure pre-ECMO ≥40 mmHg 3
Pulse pressure before ECMO ≤20 mmHg −2
HCO3 before ECMO ≤15 mmol/L −3
Constant value to add to all calculations of SAVE score −6
Lactate (mmol/dL)
– <7.5
– ≥7.5
15
0
Total score −35 to 32
Total SAVE score Risk class Survival (%)
>10 I 79
1–10 II 52
−4 to 0 III 32
−10 to −5 IV 10
≤−10 V 4

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