Issue |
J Extra Corpor Technol
Volume 44, Number 3, September 2012
|
|
---|---|---|
Page(s) | 134 - 138 | |
DOI | https://doi.org/10.1051/ject/201244134 | |
Published online | 15 September 2012 |
Original Articles
Our Experience with Two Cardioplegic Solutions: Dextrose versus Non-Dextrose in Adult Cardiac Surgery
* North Shore-LIJ Health System, Great Neck, New York
† North American Partners in Anesthesia, Melville, New York
‡ Hofstra North Shore-LIJ School of Medicine, Hempstead, New York
§ Albert Einstein College of Medicine, Bronx, New York
‖ The Feinstein Institute for Medical Research, Manhasset, New York
Address correspondence to: Renee Pekmezaris, PhD, Vice President, Department of Population Health, North Shore-LIJ Health System, 175 Community Drive, Great Neck, NY 11021. E-mail: rpekmeza@nshs.edu
Received:
12
March
2012
Accepted:
8
July
2012
Intraoperative hyperglycemia has been observed to be associated with increased morbidity and mortality after cardiac surgery. Dextrose cardioplegia is used for its cardioprotective effects but may lead to intraoperative hyperglycemia and more postoperative complications. This was a retrospective observational study. Patient records (n = 2301) were accessed from a large database at a tertiary care facility. The two groups (dextrose vs. nondextrose) were then matched using preoperative variables of age, sex, body mass index, wound exposure time, preoperative HbA1c levels, renal failure, hypertension, and prior cerebrovascular disease. The following outcomes were recorded: 30-day mortality, sternal wound infection, stroke, and highest glucose level on cardiopulmonary bypass. The dextrose cardioplegia group showed statistically higher intraoperative glucose levels (272.76 ± 55.92 vs. 182.79 ± 45, p value = .0001). There was no difference in postoperative mortality, sternal wound infections or stroke incidence, nor in other secondary outcomes. The type of cardioplegia solution was shown to affect glucose levels; however, there was no effect on postoperative complication rates.
Key words: hyperglycemia / cardiac surgery / postoperative complications / stroke / cardiac anesthesia
© 2012 AMSECT
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.