| Issue |
J Extra Corpor Technol
Volume 57, Number 4, December 2025
|
|
|---|---|---|
| Page(s) | 263 - 269 | |
| DOI | https://doi.org/10.1051/ject/2025048 | |
| Published online | 17 December 2025 | |
Review Article
Effects of hyperoxia in pediatric perfusion patients: a scoping review
Emory University Perfusion Program, Atlanta, GA 30322, USA
* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.
Received:
8
March
2025
Accepted:
12
August
2025
Abstract
Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation between these adverse effects and hyperoxia during cardiac surgery, definitions of “hyperoxia’ vary across the literature. This scoping review synthesizes findings from PubMed, CINAHL, Embase, and Web of Science to categorize the adverse effects of hyperoxia based on age range, presence of cyanosis, and PaO2 levels. The results highlight the need for standardized oxygenation management protocols in pediatric bypass procedures and a consistent definition of “hyperoxia” for cyanotic and acyanotic patients.
Key words: Cardiopulmonary bypass (CPB) / Hyperoxia / Cyanotic / Acyanotic / Pediatric / Perfusion
© The Author(s), published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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