Open Access

Table 1b

Indexed heparin and protamine dose.

1.0 Ratioa (Avg ± SD) P-value (1.0 vs 0.9) 0.9 Ratioa (Avg ± SD) p-value (0.9 vs 0.8) 0.8 Ratioa (Avg ± SD) P-value (1.0 vs 0.8)
BSA (m2) 1.97 ± 0.23 0.05 2.02 ± 0.27 0.02 1.96 ± 0.23 0.62
First Heparin Bolus (FHB, IU) 25959 ± 7003 0.16 26938 ± 7249 0.06 25693 ± 6129 0.68
APD/FHB (%) 0.67 ± 0.15 0.00 0.50 ± 0.13 0.00 0.46 ± 0.11 0.00
First Heparin Bolus/BSA(FHBi, IU/m2) 13130 ± 3919 0.59 13283 ± 2741 0.37 13056 ± 2410 0.78
Total Heparin Dose (THD, IU) 38007 ± 10823 0.33 39033 ± 10691 0.18 38427 ± 9853 0.68
APD/THD (%) 0.47 ± 0.10 0.00 0.36 ± 0.10 0.00 0.32 ± 0.7 0.00
Total Heparin Dose/BSA(THDi, IU/m2) 19220 ± 4693 0.44 19251 ± 4144 0.46 19549 ± 4056 0.94
First Hep. Conc. 3.5 ± 0.9 0.42 3.5 ± 0.7 0.94 3.5 ± 0.6 0.37
Actual Protamine Dose (APD, mg) 174 ± 53 0.00 136 ± 46 0.00 121 ± 36 0.00
APD, % Reduction from 1.0 Ratio 22% 30%
Actual Protamine Dose/BSA (APDi, mg/m2) 88 ± 22 0.00 67 ± 18 0.00 61 ± 15 0.00
APDi, % Reduction from 1.0 Ratio 24% 31%
a

Protamine:Heparin ratio expressed as (Protamine dose in mg x 100)/Heparin in IU.

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